Critical Care Rounds

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Published

Volume-Issue

Title

Total: 34

12/2006

7-4

Outcomes, Cost, and Caregiver Burden in the
Acute Respiratory Distress Syndrome (ARDS)

By MARGARET S. HERRIDGE, MS, MD, MPH, and JILL CAMERON, PhD
Patients who survive critical illness are at risk for permanent physical, functional, emotional, and neurocognitive deficits, some or all of which may contribute to a decreased health-related quality of life (HRQL).

09/2006

7-3

Noninvasive Positive Pressure Ventilation in
Critically Ill Patients: The Winds of Change?

By GABRIEL I. SUEN, MD, PETER G. BRINDLEY, MD, and MICHAEL J. JACKA, MD
Although endotracheal intubation undoubtedly saves lives, it is also associated with significant morbidity and mortality. In short, while endotracheal intubation achieves definitive airway control, it can sacrifice natural airway defense mechanisms and increase infections.

07/2006

7-2

Early Determination of Prognosis in Traumatic
Brain Injury: Beyond the Glasgow Coma Scale

By ALEXIS TURGEON, MD, MSC, FRCPC
Traumatic brain injury (TBI) is a common problem faced by intensivists. In Canada, >60% of all trauma cases are associated with brain injury and, every year, approximately 2500 of intensive care unit (ICU) admissions are related to severe TBI (ie, Glasgow Coma Scale [GCS] <9).

04/2006

7-1

Oxidative Stress in the Critically-Ill:
A Preliminary Look at the REDOXS� Study

By DAREN K HEYLAND, MD, and RUPINDER DHALIWAL, RD for the Canadian Critical Care Trials Group
The relationship between nutrient deficiency and altered immune status has been recognized for years. In critically-ill patients, nutrient deficiencies can predispose patients to impaired immune function and a higher risk of developing infectious complications, organ dysfunction, and death.

12/2005

6-5

Initial Evaluation and Management of
Severe Community-Acquired Pneumonia

By JOHN GRANTON, MD, FRCPC, and JOHN SWISTON, MD, FRCPC
Community-acquired pneumonia (CAP) remains a common cause of morbidity and mortality. In 1998, the World Health Organization (WHO) reported >3.7 million deaths from lower respiratory tract infections (RTIs) worldwide. In Canada, pneumonia and influenza are the 6th leading cause of death overall and the leading cause of death from infectious diseases.

11/2005

6-3

Reaching out beyond the ICU
By STUART REYNOLDS, MD, PIERRE CARDINAL, MD, and ALAN BAXTER, MD
There is a disturbing and pervasive body of literature suggesting that patients who are acutely ill or recovering from surgery may receive suboptimal care as changes in their status either go unrecognized or, if detected, are treated inadequately. This observation is in contrast to the current view that earlier intervention in acutely ill patients improves outcome.

07/2005

6-2

The Acute Critical Events Simulation (ACES) Program – A Novel Canadian Educational Initiative to Improve Care of the Critically Ill
BY PETER BRINDLEY, MD; DAVID NEILIPOVITZ,MD; JOHN KIM , MD; PIERRE CARDINAL , MD; AND THE ACES FACULTY
The Acute Critical Events Simulation (ACES)educational program arose from the need to address re c u rrent deficiencies in the execution of acute resuscitation. This two day course was designed by intensivists from across Canada to encourage the acquisition of knowledge, procedural skills, and especially behaviours that are essential during resuscitation of the critically ill.

04/2005

6-1

New-Onset Atrial Fibrillation in the Intensive Care Unit: An underappreciated yet common phenomenon
By SALMAAN KANJI, Pharm. D.
Atrial fibrillation (AF) is the most common dysrhythmia in adults. Prevalence increases with age from <1% in those <60-years-old to >8% in those >80-years-old. Literature describing the epidemiology, outcomes, and treatment of AF in non-critically ill patients is extensive.

01/2004

5-1

Anemia in the critically-ill patient: An examination of the rationale for recombinant erythropoietin
By JEFFREY M. SINGH, MD, FRCPC, and RANDY S. WAX, MD, FRCPC
Anemia frequently complicates the course of patients admitted to the intensive care unit (ICU) and is a common cause for red blood cell (RBC) transfusion.

11/2003

4-9

Fluid Resuscitation in the Early Management of Septic Shock
By LAURALYN McINTYRE, M.D.
Severe sepsis and septic shock are the most common causes of mortality in the intensive care unit (ICU), and account for approximately 10% of ICU admissions and 2.9% of all hospital admissions.

10/2003

4-8

High-frequency ventilation
By JEFFREY M SINGH, MD, FRCPC, and THOMAS E STEWART MD, FRCPC
Modes of high-frequency ventilation (HFV) are characterized by high respiratory rates and tidal volumes that are lower than those used in conventional mechanical ventilation (CMV).

09/2003

4-7

Vasopressin
BY CHERYL L. HOLMES, MD; DONALD W. LANDRY, MD
Arginine vasopressin (hereafter referred to as “vasopressin”), also known as antidiuretic hormone, is essential for survival as attested by its teleological persistence.

09/2003

4-6

Glycemic control in the critically ill – How sweet it is
By DEAN CHITTOCK MD, FRCPC, MS (EPID); WILLIAM HENDERSON, MD; VINAY DHINGRA, MD, FRCPC; JUAN RONCO, MD, FRCPC
The acute stress and injury that occurs in association with a critical illness results in a homeostatic response orchestrated by systemic metabolic and hormonal reactions.

06/2003

4-5

Cardiopulmonary resuscitation – When to start, when to stop
BY PETER G. BRINDLEY, MD, FRCPC
Cardiopulmonary resuscitation (CPR) has the power to prevent premature death. Sadly, however, it can also prolong inevitable death, family duress, patient suffering in the short-term and unacceptable disability in the long-term.

05/2003

4-4

SARS in the critically ill patient
By STEPHEN LAPINSKY, MD, LAURA HAWRYLUCK MD, and RANDY WAX, MD
SARS, first recognized in late 2002, has now been documented in 26 countries worldwide, with significant outbreaks in China, Hong Kong, Singapore, and Toronto.

04/2003

4-3

Medical informatics in the intensive care unit: An overview of technology assessment
By NEILL ADHIKARI, MD, CM, FRCPC, and STEPHEN E. LAPINSKY, MD, FRCPC
Effective patient care in the intensive care unit (ICU) depends on the ability of clinicians to process large amounts of clinical and laboratory data.

03/2003

4-2

Evolving concepts of sedation in the critically ill
By GEETA MEHTA, M.D.
Sedatives are an integral tool in the management of critically ill patients. However, we are only starting to appreciate that the level of sedation we provide, and when and how to stop it, are important factors in determining patient outcome in the ICU.

02/2003

4-1

Recombinant human activated protein C for treatment of severe sepsis: Therapeutic and economic considerations
By ROBERT FOWLER, MD, MS(Epi)
Sepsis is characterized by a systemic inflammatory and procoagulant response to infection. When sepsis is accompanied by dysfunction of one or more vital organs, the condition is called severe sepsis.

12/2002

3-10

Identifying the patient-at-risk: Technology and ICU Outreach Services
By DAMON C. SCALES, MD, FRCPC; WILLIAM J. SIBBALD, MD, FRCPC, FCCHSE
The provision of intensive care to critically-ill patients is a costly endeavour. Intensive care units (ICUs) account for approximately 10% of inpatient acute-care beds in the United States, and this proportion is expected to increase as our population ages.

11/2002

3-9

Renal replacement therapy in the critically ill
BY R. T. NOEL GIBNEY, MB, FRCPC
Acute renal failure (ARF) requiring renal replacement therapy (RRT) occurs in 4%-6% of patients admitted to critical care units.

10/2002

3-8

Pulmonary embolism: The clot stops here
By JOHN GRANTON, MD
In the face of advances in prophylaxis, therapy, and diagnostic strategies/methods, acute pulmonary embolism (aPE) remains a common cause of morbidity and mortality in Canada.

08/2002

3-7

Empiric antibiotics in the critically ill
patient: Panacea or poison?

By MARY-ANNE AARTS, MD, and JOHN MARSHALL, MD
Empiric antibiotic therapy – the administration of antibiotics before a microbiological
diagnosis of infection is established – is a widely used but unproven
practice in contemporary intensive care units (ICUs).

06/2002

3-6

Quality improvement and patient safety: How the challenge applies to critical care
By J. DEAN SANDHAM, MD, and THOMAS ROSENAL, MD
Quality of care and patient safety are undeniably primary concerns for all providers who work in critical care.

05/2002

3-5

End-of-life care: An update
GRAEME ROCKER MHSC, DM, FRCP
The last several years have seen welcome improvements in our understanding of end-of-life care in the ICU.

04/2002

3-4

The TRICC trial: A focus on the subgroup analysis
PAUL C. HÉBERT, MD, FRCPC, MHSC
Red blood cell (RBC) transfusions, administered to improve O2 delivery to the tissues, are common in critical care practice.

03/2002

3-3

Genetic predictors of adverse outcome from sepsis, ARDS and SIRS
By KEITH R. WALLEY, M. D. and JAMES A. RUSSELL, M.D.
An increasing number of articles have been appearing in the critical care literature describing associations between genetic polymorphisms and adverse outcomes in acute systemic inflammatory states, ie, sepsis and septic shock, acute respiratory distress syndrome (ARDS), and the associated systemic inflammatory response syndrome (SIRS).

02/2002

3-2

Severe traumatic brain injury:
Controversies in management

BY JAMES S. HUTCHISON, MD
Head injury is the most common cause of mortality and acquired disability in children, adolescents, and young adults, accounting for 33 new cases of disability per 100,000 people per year in the United States.

01/2002

3-1

Salt, water and cerebral edema
DESMOND BOHN, MB, BCH, FRCPC
The administration of IV fluids is probably the most commonly performed procedure in hospitalized patients.

10/2001

2-4

Advances in the management of hypotension in septic shock
CLAUDIO MARTIN, MD
Society (CCCS) ?
Editorial Board
New therapies such as recombinant human activated protein C (rhAPC) are emerging for the treatment of severe sepsis and septic shock, but fundamental aspects for management of these patients must still be applied.

08/2001

2-3

Modulation of the systemic inflammatory response in sepsis: Current status, future prospects
JOHN C. MARSHALL, MD, FRCSC
Sepsis is a complex disease process that arises through the activation of a systemic response to infection.

04/2001

2-2

Surfactant and the Acute Respiratory Distress Syndrome(ARDS)
JAMES S. LEWIS, MD, FRCPC
The Acute Respiratory Distress Syndrome (ARDS) is a pulmonary complication resulting from a variety of initial insults, all of which involve an overwhelming inflammatory response within the host.1,2

11/2000

1-3

Sedation in the Critical Care Unit
SEAN P. KEENAN, MD,
Those familiar with the care of critically ill patients know that anxiety and agitation is expected in these patients due to the stress they are suffering.

09/2000

1-2

The acute respiratory distress syndrome (ARDS)
JOHN GRANTON, MD
Since the original description of the acute respiratory distress syndrome (ARDS) by Ashbaugh and colleagues, basic questions about its definition, incidence and pathophysiological characteristics are being revisited.

07/2000

1-1

Ventilator-associated pneumonia:
Daren Heyland, MD
Current management strategies

Total: 34